About SYSDIET

The prevalence of obesity, insulin resistance (IR), and type 2 diabetes mellitus (T2DM) is increasing rapidly worldwide due to westernised dietary habits, obesity and sedentary lifestyle. Type 2 diabetes is preventable by beneficial lifestyle - especially by dietary changes. The basic mechanisms by which dietary factors are involved in the pathogenesis of obesity, insulin resistance, metabolic syndrome, type 2 diabetes and cardiovascular diseases are, however, poorly understood.

To develop new strategies for dietary prevention of these conditions, we need knowledge on the interactions of genetic and diet-related early changes in metabolism. Nutrition related early biomarkers can assist in identifying individuals at high risk in early stages of disease pathogenesis. To find the biomarkers, research on interactions at the physiological, cellular and genetic levels is needed. If successful, this can lead to personalised dietary counselling and direct development of new targeted healthy foods for prevention of disease.

SYSDIET will produce high quality and innovative information on the health effects of Nordic dietary constituents promoting health and prevention of chronic diseases. Dietary means seldom have side effects and have in many cases also shown to be cost efficient. Their potential in prevention and treatment of chronic diseases is, however, clearly under-exploited.

Updated: 27.03.2008 KK